Understanding Tuberculosis: Global Experiences and Innovative Approaches to the Diagnosis, 2012

Understanding Tuberculosis: Global Experiences and Innovative Approaches to the Diagnosis

Pere-Joan Cardona

ISBN: 9533079387

This book presents the experience of worldwide specialists on the tuberculosis diagnosis, along with its lights and shadows.

Mycobacterium tuberculosis is a disease that is transmitted through aerosol. This is the reason why it is estimated that a third of humankind is already infected by Mycobacterium tuberculosis. The vast majority of the infected do not know about their status. Mycobacterium tuberculosis is a silent pathogen, causing no symptomatology at all during the infection. In addition, infected people cannot cause further infections. Unfortunately, an estimated 10 per cent of the infected population has the probability to develop the disease, making it very difficult to eradicate. Once in this stage, the bacilli can be transmitted to other persons and the development of clinical symptoms is very progressive.

Therefore the diagnosis, especially the discrimination between infection and disease, is a real challenge.

Contents

Part 1 Experience on Laboratory diagnosis around the World

1 Clinical Laboratory Diagnostics for Mycobacterium tuberculosis

2 Laboratory Diagnosis of Latent and Active Tuberculosis Infections in Trinidad a Tobago and Determination of Drug Susceptibility Profile of Tuberculosis Isolates in the Caribbean

3 Tuberculosis is Still a Major Challenge in Africa

4 Tuberculosis in Saudi Arabia

5 Diagnosis of Mycobacterium tuberculosis

6 Diagnosis of Smear-Negative Pulmonary Tuberculosis in Low-Income Countries: Current Evidence in Sub-Saharan Africa with Special Focus on HIV Infection or AIDS

7 Immunologic Diagnosis of Neurotuberculosis

8 Diagnostic Methods for Mycobacterium tuberculosis and Challenges in Its Detection in India

9 Management of TB in HIV Subjects, the Experience in Thailand

10 Mycobacterium tuberculosis: Biorisk, Biosafety and Biocontainment

Part 2 New approaches to the TB diagnosis

11 New Diagnostics for Mycobacterium tuberculosis

12 Nanodiagnostics for Tuberculosis

13 Sputum Smear Microscopy for Tuberculosis: Evaluation of Autofocus Functions and Automatic Identification of Tuberculosis Mycobacterium

14 The Use of Phage for Detection, Antibiotic Sensitivity Testing and Enumeration

15 Molecular Imaging in TB: From the Bench to the Clinic

16 Data Mining Techniques in the Diagnosis of Tuberculosis

17 Immunological Diagnosis of Active and Latent TB

18 Immune Diagnosis of Tuberculosis Through Novel Technologies

19 Exosomes: New Tuberculosis Bio markers - Prospects From the Bench to the Clinic

20 Molecular Techniques for Identification of Species of the Mycobacterium tuberculosis Complex: The use of Multiplex PCR and an Adapted HPLC Method for Identification of Mycobacterium bovis and Diagnosis of Bovine Tuberculosis

Part 3 Improving detection and control of resistances

21 Survey and Molecular Characterization of Drug- Resistant M. tuberculosis Clinical Isolates from Zunyi, Guizhou Province of China

22 Molecular Biological Techniques for Detection of Multidrug Resistant Tuberculosis (MDR) and Extremely Drug Resistant Tuberculosis (XDR) in Clinical Isolates of Mycobacterium tuberculosis

23 Detection of Mycobacterium tuberculosis and Drug Resistance: Opportunies and Challenges in Morocco

24 Pattern of Circulating Mycobacterium tuberculosis Strains in Sri Lanka

25 Health Interventions to Improve the Medication Efficacy in Tuberculosis Treatment

dOWNLOAd .




  .